Space, Time and Motion in Czech as a Second Language

72

Mechanical design of plastic parts crusher

Tato bakalářská práce se zabývá návrhem drtičky plastových dílů, vyráběných pomocí 3D tisku. Cílem práce je navrhnout konstrukci drtičky, jejíž výstupní frakci tzv. granulát je možno použít pro výrobu recyklované struny. První část práce je tvořena analýzou současného stavu technologie drcení. Dále jsou určeny vlastnosti drceného materiálu a definovány požadavky na kvalitu výstupního granulátu. Na základě zhodnocení poznatků z rešerše jsou vytvořeny parametry, jež by měla vhodná konstrukce drtičky splňovat. Dle těchto parametru je navrhnuto několik variant, z nichž je vybráno finální řešení – dvojstupňová drtička, která je v poslední části práce zkonstruována.The thesis focuses on the construction of shredder of plastic components produced by 3D printers. The aim of the thesis is to design a shredder whose output components, the so-called flakes, could be used to produce recycled filament. The first part of the thesis covers an analysis of technology of shredding. Furthermore, the properties of shredded material and the requirements for the quality of output granules are determined. Based on the research, the parameters for the efficient shredder are defined. In accordance with these parameters, several variants are created, from which the final design of the two-stage shredder is selected and constructed.

Úvodní slovo

5

Secretory glands in cercaria of the neuropathogenic schistosome Trichobilharzia regenti - ultrastructural characterization, 3-D modelling, volume and pH estimations

<p>Abstract</p> <p>Background</p> <p>Cercariae of schistosomes employ bioactive molecules for penetration into their hosts. These are released from specialized unicellular glands upon stimuli from host skin. The glands were previously well-described in the human pathogen <it>Schistosoma mansoni</it>. As bird schistosomes can also penetrate human skin and cause cercarial dermatitis, our aim was to characterize the architecture and ultrastructure of glands in the neurotropic bird schistosome <it>Trichobilharzia regenti </it>and compare it with <it>S. mansoni</it>. In the context of different histolytic enzymes used by these two species, we focused also on the estimations of gland volumes and pH in <it>T. regenti</it>.</p> <p>Results</p> <p>The architecture and 3-D models of two types of acetabular penetration glands, their ducts and of the head gland are shown here. We characterized secretory vesicles in all three gland types by means of TEM and confirmed accuracy of the models obtained by confocal microscopy. The results of two independent approaches showed that the glands occupy ca. one third of cercarial body volume (postacetabular glands ca. 15%, circumacetabular 12% and head gland 6%). The inner environment within the two types of acetabular glands differed significantly as evidenced by dissimilar ability to bind fluorescent markers and by pH value which was higher in circumacetabular (7.44) than in postacetabular (7.08) glands.</p> <p>Conclusions</p> <p>As far as we know, this is the first presentation of a 3-D model of cercarial glands and the first exact estimation of the volumes of the three gland types in schistosomes. Our comparisons between <it>T. regenti </it>and <it>S. mansoni </it>implied that the architecture and ultrastructure of the glands is most likely conserved within the family. Only minor variations were found between the two species. It seems that the differences in molecular composition have no effect on general appearance of the secretory cells in TEM. Fluorescent markers employed in this study, distinguishing between secretory vesicles and gland types, can be useful in further studies of mechanisms used by cercariae for host invasion. Results of the first attempts to estimate pH within schistosome glands may help further understanding of regulation of enzymatic activities present within the glands.</p

Aplikovaná lingvistika : příručka pro studenty Bc. studia ČJL

První česká učebnice zaměřená na oblast aplikované lingvistiky, z jejíhož širokého záběru si vybírá několik klíčových témat: osvojování prvního a druhého jazyka, učení se cizímu jazyku, problematiku chybové analýzy, forenzní lingvistiku a analýzu diskurzu. Publikace čtenáře uvádí do dynamicky se rozvíjející problematiky výstavby akvizičních korpusů a představuje akviziční korpusy, které jsou dostupné pro češtinu. Učebnice je určena pregraduálním studentům lingvistických, filologických a učitelských studijních oborů se zájmem zejména o osvojování jazyka a učení se jazyku a o analýzu diskurzu

Deverbal Noun Predicates of Czech Do-Constructions in a Cross-Linguistic Perspective

18819

Experimental Evaluation of Modified Groundhook Car Suspension with Fast Magnetorheological Damper

The car suspension setting is always a trade-off between comfort and handling. The semi-active damper system seems to be an option for reducing the compromise between the two demands. This paper deals with the effect of the magnetorheological damper setting on a car’s suspension performance, especially tire grip, which was directly measured. A unique test rig was developed, and an experimental trolley with a fast magnetorheological damper (response time of 3 µs) was used in the paper. The damper was controlled by a modified Groundhook algorithm. Compared with the passive regime, the experiments showed a 30% improvement when using the Groundhook algorithm and when the damper was adequately set. The experiments proved the trends that were set by simulations